Revisiting the Hygiene Hypothesis: Spotlight on Parasitic Hookworm Infections and Autoimmune and Allergic Disease
The hygiene hypothesis proposes that the rising incidence of autoimmune and allergic disease may be associated with improved sanitation, less incidence of childhood infections as well as chronic parasitic infections in the developed world.
Since Strachan first proposed the theory in 1989, the hygiene hypothesis may lead to novel therapies for autoimmune and allergic disease treatment and prevention, however; ongoing debate still exists as to whether infections help prevent or induce autoimmune disease (1).
But could they possibly prevent autoimmune and allergic disease?
Necator americanus (hookworm) and other helminth infections such […]