Fast Caffeine Metabolizers Can Still Be Sensitive to Coffee – Here’s Why

You may know someone who seems to be able to drink all of the caffeine they want and sleep like a baby each night.

For others, a sip of coffee taken after lunch could give them insomnia all night.

Caffeine is metabolized by a liver enzyme coded by the gene CYP1A2. If you carry 1 or two “bad” copies of this gene, it will slow your ability to process your caffeine intake – and you may be more sensitive than someone else.

Chris Kresser, LAc recently made an excellent review of how coffee can be good or bad for you based on whether you are a fast or slow metabolizer of caffeine. According to Kresser, slow metabolizers of caffeine may be at higher risk of heart disease, high […]